Consideration 5 - How Many Ingredients Are There In Breastmilk?
“Evolutionary biologists hypothesize that lactation evolved over 200 million years to provide infants with both immunologic and nutritional support. This rich secretion contains antimicrobial, anti-inflammatory and immunomodulatory factors that serve to compensate for many aspects of the infant’s functional immune immaturity…
Breast milk is a remarkably ‘altruistic’ secretion; that is, its contents are directed at protecting the infant with minimal or no benefit to the mother…
In addition to antibodies, breast milk contains more than 100,000 constituents, which can influence the growth, development and immune status of the infant.” http://www.medscape.com/viewarticle/814970
“TABLE 1 Anti-infective and immunological components in human milk
Adaptive immunity compounds: Immunoglobulins sIgA (11S), 7S IgA, IgG, IgM, IgE, IgD, free secretory component, antidiotypes
Innate immunity agents: Complement, chemotactic factors, properdin factors, interferon, a-fetoprotein, antistaphylococci factors, mannose binding lectin, b-defensin-1, antiadherence substances (oligosaccharides, mucins, lactadherin, glycolipids and glycosaminoglycans, k-casein), milk fat globule, hormones and growth factors (prolactin, cortisol, insulin, thyroxin, prostaglandins, vascular-endothelial growth factor, nerve growth factor, TGF, erythropoietin), antiviral factors (fatty acids and monoglycerides),migration inhibition factor, a-lactalbumin
Cytokines, chemokines, and receptors: IL-1b, IL-2, IL-4, IL-5, IL-6, IL-8, IL-12, IL-13, IL-16, IL-18, IFNg, TNFa, G-CSF, M-CSF, GM-CSF, GROa, monocyte chemotactic protein-1, TGFb1 and -2, sCD14, Toll-like receptor, sFas, sFasL
Anti-inflammatory factors: IL-10, TGFb2, glucocorticoids, antioxidants (a-tocopherol, b-carotene, lutein, vitamin E, catalase, glutathione peroxidase,), lactoferrin, IL-1Ra, soluble TNFa receptors I and II, CD59
Prebiotics: Bifidus factor, oligosaccharides
Carrier proteins: Lactoferrin, transferrin, vitamin B-12 binding protein, steroid binding protein.
Enzymes: Lysozyme, lipoproteinlipase, leukocyte enzymes, antiproteases, platelet-activating factor-acetyl-hydrolase
Others: Nucleotides, long-chain polyunsaturated fatty acids
Cellular – Total counts: Colostrum, 1–3 3 109/L; mature milk, ;1 3 108/L
Cell types: Macrophages, 60%; neutrophils, 25%; lymphocytes, 10%; epithelial cells”
About 75 million years ago humans and goats evolved into separate species. For 125 million years milk was evolving in a common ancestor.
These 100,000 ingredients have to be viewed as beneficial or benign. Negative ingredients would cause negative results and the individuals involved would not be as likely to live or succeed in gaining a mate and reproducing.
Evolution remembers beneficial ingredients in the genetic code, because they improve the infant’s chances of survival. Milk is best at building bones, brains, livers, muscles, kidneys and the other body parts. Milk as a food, is far above other foods in nutritional quality and diversity.
The discovery of the complexity of milk has happened in the last 25 years. What an awesome creation that was made by evolution. It is beneficial beyond belief. Created and improved to increase survival, provide water and nutrients. Milk could be one of the most complex things in the world.